| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 03-10-25 19:00 | NAC Breda | FC Groningen | 1:2 |
| 04-10-25 15:30 | Sparta Roterdão | Ajax Amsterdão | 3:3 |
| 04-10-25 17:45 | Fortuna Sittard | FC Volendam | 1:0 |
| 04-10-25 19:00 | PEC Zwolle | PSV Eindhoven | 0:4 |
| 04-10-25 20:00 | SC Heerenveen | Excelsior Roterdão | 2:1 |
| 05-10-25 11:15 | FC Twente Enschede | Heracles Almelo | 2:1 |
| 05-10-25 13:30 | Feyenoord Rotterdão | FC Utrecht | 3:2 |
| 05-10-25 15:45 | AZ Alkmaar | Telstar | 2:1 |
| 05-10-25 19:00 | Go Ahead Eagles Deventer | NEC Nijmwegen | 1:1 |